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Research

Our goal is to support the work of our faculty, researchers, and investigators by fostering collaboration and innovation.
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Examples of recent work include:

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Mutational Scanning

Rare Variant Exploration

Lead Researchers

  • Doug Fowler

  • Lea Starita

  • Andrew Stergachis

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Sea Hub

The Brotman Baty Institute & The Seattle Hub for Synthetic Biology

Lead Researchers

  • Jay Shendure,  

  • Cole Trapnell,  

  • Marion Pepper,  

  • Sud Pinglay,  

  • Nobuhiko (Nobu) Hamazaki

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Single Cell Sequencing

Single Cell Atlases

Lead Researchers

  • Cole Trapnell

  • Jay Shendure

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Genomics

BBI Advanced Technology Lab

Lead Researchers

  • Lea Starita

  • Jay Shendure

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Mutational Scanning

Variant Effects Program

Lead Researchers

  • Lea Starita,  

  • Doug Fowler,  

  • Jay Shendure,  

  • Andrew Stergachis

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Infectious Diseases

Historic Landmark BBI Study: Seattle Coronavirus Assessment Network

Lead Researchers

  • Helen Chu,  

  • Trevor Bedford,  

  • Jay Shendure,  

  • Lea Starita,  

  • Debbie Nickerson,  

  • Christina Lockwood,  

  • Janet Englund,  

  • Alpana Waghmare,  

  • Cécile Viboud,  

  • Barry Lutz,  

  • Michael Boeckh

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Infectious Diseases

Historic Landmark BBI Study: Seattle Flu Study

Lead Researchers

  • Helen Chu,  

  • Trevor Bedford,  

  • Michael Boeckh,  

  • Barry Lutz,  

  • Janet Englund,  

  • Jay Shendure,  

  • Lea Starita,  

  • Debbie Nickerson,  

  • Christina Lockwood,  

  • Alpana Waghmare,  

  • Cécile Viboud

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Infectious Diseases

Historic Landmark BBI Study: UW Husky Coronavirus Testing Study

Lead Researchers

  • Helen Chu,  

  • Lea Starita,  

  • Trevor Bedford,  

  • Debbie Nickerson,  

  • Christina Lockwood

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Genomics

Historic Landmark BBI Study: Connect My Variant

Lead Researchers

  • Brian Shirts

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Infectious Diseases

Historic Landmark BBI Study: Seattle Flu Alliance

Lead Researchers

  • Helen Chu,  

  • Trevor Bedford,  

  • Lea Starita,  

  • Jay Shendure,  

  • Christina Lockwood,  

  • Janet Englund,  

  • Michael Boeckh,  

  • Alpana Waghmare,  

  • Cécile Viboud,  

  • Barry Lutz,  

  • JT McCrone,  

  • Ana Weil

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Genomics

Historic Landmark BBI Study: SeqFirst

Lead Researchers

  • Mike Bamshad,  

  • Ghayda Mirzaa,  

  • Jessica Chong,  

  • Katrina Dipple,  

  • Dan Doherty,  

  • David Veenstra

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Sea Hub

SeaBridge

Lead Researchers

  • Jay Shendure

  • Marion Pepper

  • Cole Trapnell

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